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KMID : 0363220100480121114
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Korean Journal of Dermatology
2010 Volume.48 No. 12 p.1114 ~ p.1117
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Kappa Chain Monoclonal Primary Cutaneous Plasmacytoma
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Chung Ki-Hun
Lee Min-Jung
Ko Dong-Kyun
Park Joon-Soo
Chung Hyun
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Abstract
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Primary cutaneous plasmacytoma is a rare type of cutaneous B-cell lymphoma that arises primarily in the skin, and this is derived from clonally expanded plasma cells with various degrees of maturation and atypia. A 72-year-old man had an asymptomatic, solitary reddish to violaceous nodule on the back for about 4 months. The histologic finding of the skin biopsy specimen demonstrated an infiltration of variably matured plasma cells in the dermis, and these cells showed a monotypic expression of immunoglobulin kappa chains on immunohistochemical staining. Staging investigations excluded any extracutaneous manifestations of the disease. Only a few cases of primary cutaneous plasmacytoma have been published in the Korean dermatologic literature. Herein, we report on an interesting case of primary cutaneous plasmacytoma with monoclonality of kappa chains.
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KEYWORD
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Kappa chain, Monoclonality, Primary cutaneous plasmacytoma
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